DROSOPHILA S2 CELLS ARE NON-PERMISSIVE FOR VACCINIA VIRUS DNA REPLICATION FOLLOWING ENTRY VIA LOW PH-DEPENDENT ENDOCYTOSIS AND EARLY TRANSCRIPTION.

Drosophila S2 cells are non-permissive for vaccinia virus DNA replication following entry via low pH-dependent endocytosis and early transcription.

Vaccinia virus (VACV), a member of the chordopox subfamily of the Poxviridae, abortively infects insect cells.We have investigated VACV infection of Drosophila S2 cells, which are useful for protein expression and genome-wide RNAi screening.Biochemical and electron microscopic analyses indicated that VACV entry into Drosophila S2 cells depended on

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Polymorphisms within the TNFSF4 and MAPKAPK2 Loci Influence the Risk of Developing Invasive Aspergillosis: A Two-Stage Case Control Study in the Context of the aspBIOmics Consortium

Here, we assessed whether 36 single nucleotide polymorphisms (SNPs) within the TNFSF4 and MAPKAPK2 loci influence the risk of developing invasive aspergillosis (IA).We conducted a two-stage case control study including 911 high-risk patients diagnosed with hematological malignancies that were ascertained through the aspBIOmics consortium.The meta-a

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A Novel Machine-Learning Framework Based on a Hierarchy of Dispute Models for the Identification of Fish Species Using Multi-Mode Spectroscopy

Seafood mislabeling rates of approximately 20% have been reported globally.Traditional methods for fish species identification, such as DNA analysis and polymerase chain reaction (PCR), are expensive and time-consuming, and require skilled technicians and specialized equipment.The combination of spectroscopy and machine learning presents a promisin

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